Begin with an online pre-quiz about West Nile Virus. Using a fictional scenario, young epidemiologists read how it is transmitted and examine the stages of the life cycle of a mosquito. They imagine that they are members of the Centers for Disease Control and Prevention, formulating plans for identifying infected persons and how to contain the spread of the virus. The 35-page lesson plan provides beneficial background information, worksheets, resource links, answer keys to ensure success at teaching this mini-unit to your biology masters.