Hank shares some developments in cancer research, from new insights into the behavior of zombie cancer cells, to a new method that uses nanotechnology to kill cancer from within.

Hank shares some developments in cancer research, from new insights into the behavior of zombie cancer cells, to a new method that uses nanotechnology to kill cancer from within.

We just learned about hydrogenation of alkenes via homogeneous catalysis, and the complicated catalytic cycles that are involved. But there is an additional aspect that we need to discuss. Whenever possible, we want to be able to employ...

Now that we understand the goal of transition metal catalysis, it's time to look at the two main ways in which this is achieved. There is homogeneous catalysis and heterogeneous catalysis. Let's focus on homogeneous catalysis first,...

How to Determine Reactiveness/Lability of a Metal

Hill Coefficients

Before we can discuss the types of reactions that transition metal complexes can participate in, we need to discuss more of their properties. In this video, we will review the Crystal Field Theory and build on it to explore the Ligand...

The Trans-Effect: Example 1

Before we dive into the applications of organometallic reactions, let's look at one more type of reaction: metathesis. In metathesis reactions, two bonds will break and two bonds will form. Let's look at some of these possibilities!

Migratory insertions are very different than the first three types of organometallic reactions we have looked at. For example, this process is only possible with ligands that are cis to one another. Let's look at how this works!

Researchers have come up with a potential new method of harvesting uranium - the fuel source for nuclear power - from seawater. Scientists at the 224th meeting of the American Chemical Society reported that when Chitin - a long-chain...

Now that we know some things about immune cell structure and function, we need to start understanding how these cells interact on the molecular level, and how signals are translated into cellular response. This means looking at...

Now that we've made it through the periodic table, it's time to look at transition metals and the coordination compounds they can form. What types of ligands can they interact with, and how? What shapes do they make? There is so much to...

Lesson on the Non-Canonical NF-kB Signaling pathway.

The Noncanonical NFkB signaling pathway is primarily involved in B cell maturation, lymphoid organogenesis and immune system functioning. This signaling pathway differs from the...

Ok, so we understand how ligands bond to metals to form transition metal complexes, but how many ligands will fit? Well, remember the octet rule from general chemistry? There is a similar concept that we can apply here, which is called...

We've covered the basics regarding ligands that can be found in transition metal complexes. But it gets quite a bit trickier than that. What about polyhapto ligands? Bridging ligands? Polydentate ligands? What could all of this mean?...

We just learned how to use the 18 electron rule, so let's get some more practice with a few trickier examples!

The Trans-Effect: Example 2

In addition to ligand exchange, another common organometallic reaction is oxidative addition. This commonly occurs with metals that have stable oxidation states that are two apart. Let's explore some examples of different stypes of...

Reductive elimination is essentially the opposite of oxidative addition and the products of one process can be the reactants of the other process. What conditions are most favorable to reductive elimination?

Reactions that occur on the ligands themselves are quite common. Let's look at two common types of ligand reactions: nucleophilic and electrophilic attacks. Which types of ligands that are susceptible to these attacks and what happens?

In previous videos, we have discussed complexes with a single metal center, but in this video we will focus on polynuclear transition metal complexes. Let's go through a couple examples and review how to check that the 18-electron rule...

JAK STAT Signaling Pathway Lesson: Ligands, Receptors, and Importance in Disease.



Hey guys! In this lesson, you will learn the JAK STAT signaling pathway, the ligands that activate the pathway, the cell surface receptors...

It's finally time to look at organometallic reactions! We'll start with ligand substitution, which involves the equal exchange of one or more ligands. Then, we'll introduce the Trans Effect and Cis Effect, both of which deal with how...